Hydroxyapatite Toothpaste Side Effects: Uncovering the Truth

Generally, hydroxyapatite toothpaste is considered safe for most individuals, with minimal risk of side effects. This is supported by various studies (which we'll get into a little later in this article!) that consistently report zero adverse health effects associated with hydroxyapatite toothpaste.

This finding is in direct contrast with fluoride which, when consume in excess, has been linked with various potential side effects such as:

  • dental fluorosis

  • skeletal fluorosis

  • fluoride intoxication

  • and neurological issues.

That's why many people consider hydroxyapatite toothpaste better than fluoride.

In this article, we will uncover the truth behind hydroxyapatite toothpaste and its potential side effects to help you make informed decisions about your oral health.

What is hydroxyapatite?

A woman brushing her teeth

Hydroxyapatite (also referred to as simply "HA") is a naturally occurring mineral that is the primary inorganic component of human teeth and bones.

It is a crystalline structure composed of calcium and phosphate ions, making it a vital component of the hard tissues in our bodies. In fact, hydroxyapatite gives our teeth and bones their strength and hardness.

In the context of teeth, hydroxyapatite is a key component of tooth enamel, which is the outermost layer of the tooth surface. Enamel is the hardest substance in the human body, and it protects the underlying dentin and pulp of the tooth.

Hydroxyapatite is also used in various dental and medical applications, including dental implants, bone grafts, and as a biomaterial in orthopedic surgery.

Further, in hydroxyapatite toothpaste, it has restorative properties that are not limited to its protective barrier alone; it also contributes significantly to the remineralization process, aiding in the repair of microscopic enamel imperfections that are otherwise invisible to the naked eye.

What is hydroxyapatite toothpaste?

Hydroxyapatite used in many forms including toothpaste, it is an innovative oral care product that harnesses the power of hydroxyapatite, a naturally occurring mineral found in your tooth enamel surface.

These hydroxyapatite toothpastes work by depositing calcium and phosphate ions back into your tooth surfaceResearch has shown that this can make your teeth stronger and help fill in minerals, which is good for your dental health.

It offers a fluoride-free alternative for maintaining your optimal oral health, making it suitable for individuals with fluoride sensitivities.

Additionally, hydroxyapatite toothpaste tablets are just equally as effective as traditional toothpaste but offer the added benefits of being better for the environment and more convenient for travel due to their compact and mess-free nature.

How does hydroxyapatite toothpaste work?

Hydroxyapatite toothpaste works through its ability to stimulate a process called remineralization. Essentially, hydroxyapatite particles restore and strengthen our tooth enamel by depositing calcium phosphate ions.

You see, when our enamel is exposed to acids produced by the bacteria that naturally live in our mouths or dietary acids/sugars, it can become demineralized. This leads to weakened enamel, tooth sensitivity, and tooth decay. If left untreated, that tooth decay can progress into full blown dental caries.

Since hydroxyapatite is a biomimetic compound and closely mimics the natural mineral composition of our teeth, it is easily able to remineralize enamel and protect us from all kinds of dental issues.

Plus, studies also show that hydroxyapatite toothpaste can prevent plaque buildup which can otherwise lead to tartar development and cavities. Further, more research suggests that hydroxyapatite can also whiten teeth as the tooth remineralization process may remove surface stains.

Why is hydroxyapatite used in toothpaste?

Hydroxyapatite is used in toothpaste because of its effectiveness in strengthening enamel and reversing early dental caries.

As a calcium-based compound, synthetic hydroxyapatite is highly compatible with the human body. When used in toothpaste, it helps to remineralize and strengthen tooth enamel, making it more resistant to decay.

Additionally, studies have shown that hydroxyapatite toothpaste has comparative efficacy with fluoride toothpaste in preventing tooth decay and has the added benefit of improving tooth sensitivity, making it a versatile option for your daily oral care.

Now that you understand what hydroxyapatite is and how it works, let's review some of its benefits!

Benefits of Hydroxyapatite Toothpaste

Hydroxyapatite toothpaste tablets are making waves for all of the incredible benefits they offer for your teeth. Here in this section, we'll explore some of the most important ones.

Promotes Enamel Remineralization

A white teeth

Studies show that hydroxyapatite toothpaste promotes dental enamel remineralization, effectively repairing and strengthening your tooth enamel.

This natural mineral compound is able to reverse early enamel erosion and fight tooth decay by replenishing essential minerals, such as calcium and phosphate.

In fact, in comparing hydroxyapatite vs fluoride, hydroxyapatite toothpaste is scientifically proven to be just as effective as fluoride at remineralizing teeth.

Soothes Hypersensitivity

Hydroxyapatite toothpaste has the ability to soothe tooth sensitivity.

This toothpaste works by creating a protective layer over the exposed dentin, which reduces the transmission of external stimuli to the nerve endings, thereby lessening the pain associated with tooth sensitivity.

Plus, it can greatly enhance your ability to tolerate acidity, temperature, and sugar, ultimately improving the overall oral health and quality of life if your having dentin hypersensitivity.

Prevents Tooth Decay

a woman showing tooth cavity model

Research indicates that hydroxyapatite does indeed help prevent tooth decay.

It works by inhibiting plaque-causing bacteria and remineralizing initial caries lesions, making it an effective option for preventing tooth decay.

Compared to fluoride toothpastes, hydroxyapatite toothpaste offers a natural alternative for preventing tooth decay. It provides similar cavity prevention benefits without the potential side effects of fluoride.

Fights Plaque-Causing Bacteria

Studies indicate that hydroxyapatite toothpaste acts as a natural defense against plaque-causing bacteria, helping to prevent the formation of oral biofilm.

Unlike fluoride, hydroxyapatite has a unique antibacterial properties. By selectively killing off certain strains of bacteria that disrupt your mouth, hydroxyapatite protects your teeth and gums.

Additionally, hydroxyapatite disrupts biofilm, thereby reducing your risk of developing demineralization and gum issues.

Naturally Compatible with Your Teeth

Another remarkable benefit of hydroxyapatite toothpaste is its natural compatibility with your teeth.

Because the composition of hydroxyapatite closely resembles the minerals found in tooth enamel, it provides your teeth with the necessary minerals making it an ideal choice for maintaining healthy enamel.

Plus, unlike other toothpaste options, hydroxyapatite does not introduce foreign substances to your teeth.

Safe Alternative to Fluoride

A family brushing their teeth

If you are aware of the potential risks associated with fluoride, studies have shown that hydroxyapatite toothpaste provides a safe and effective alternative.

Fluoride toothpastes have been widely used for decades to prevent tooth decay. However, research indicates that excessive fluoride consumption, especially during early childhood, can lead to dental fluorosis and toxicity.

Hydroxyapatite toothpaste, on the other hand, does not contain fluoride, but offers comparable efficacy in reversing tooth decay, strengthening the teeth, and inhibiting the growth of plaque-causing bacteria.

Fights Dental Caries

Bacteria in Mouth

Hydroxyapatite toothpaste offers an effective solution in the fight against dental caries.

Through its unique composition, this toothpaste can remineralize and strengthen your weakened tooth structures, effectively combatting caries lesions and preventing further damage.

This preventive dentistry approach is particularly valuable in reducing the risk of tooth loss and the need for extensive dental treatments. By using hydroxyapatite toothpaste regularly, you can actively support your oral health and protect your teeth from the harmful effects of dental caries.

Promotes Good Oral Health

Hydroxyapatite toothpaste promotes good oral health by addressing various dental concerns effectively.

Studies have shown that hydroxyapatite enhances enamel remineralization, strengthens tooth structure, and inhibits the growth of plaque-causing bacteria.

It has a natural antibacterial properties contribute to a healthier oral environment, reducing the risk of gum disease and other oral infections.

Therefore, by incorporating hydroxyapatite toothpaste into your daily oral care routine, you can effectively protect your gums, prevent oral diseases, and maintain strong, healthy teeth.

Brightens Teeth

Hydroxyapatite toothpaste also offers the benefit of brightening teeth through its gentle and effective stain removal properties.

In vitro study states that hydroxyapatite toothpaste effectively removes surface stains from teeth, resulting in a brighter and whiter smile.

Unlike abrasive whitening toothpaste that may contain SLS and can cause enamel damage, hydroxyapatite toothpaste gently polishes the teeth, revealing their natural brightness without compromising enamel integrity.

This fluoride-free toothpaste is an excellent option for people with sensitive teeth who may experience discomfort or sensitivity when using traditional whitening products.

To experience the brightening effects of hydroxyapatite toothpaste, incorporate it into your daily oral care routine. Brushing your teeth twice a day with this natural toothpaste can help you achieve a radiant smile while promoting overall oral health.

Stabilizes Your Oral pH

Hydroxyapatite toothpaste offers the distinct advantage of stabilizing your oral pH, contributing to a healthier mouth environment.

Research indicates that hydroxyapatite is resistant to acid, allowing it to effectively buffer the pH levels in your mouth. This means that even when acidic substances are consumed, such as citrus fruits or carbonated beverages, hydroxyapatite can help maintain a more neutral pH, reducing the risk of enamel erosion and promoting overall oral health.

By stabilizing your oral pH, hydroxyapatite toothpaste aids in preserving tooth enamel and minimizing the likelihood of dental issues like cavities and tooth sensitivity.

Therefore, incorporating hydroxyapatite toothpaste into your oral care routine can lead to a more balanced and resilient oral environment, supporting long-term dental wellness.

Side Effects of Hydroxyapatite Toothpaste

A woman brushing her teeth

Hydroxyapatite toothpaste is generally considered safe for most individuals, with minimal risk of side effects.

Research states that there is no literature reporting any systemic or adverse effects of hydroxyapatite containing toothpastes. One paper even states: "Thus far in the literature, there have been no reports of adverse dental or systemic effects of HAP-containing toothpastes because HAP has an excellent biocompatibility".

Further, one study found that hydroxyapatite nanoparticles possess no irritation potential, meaning they're gentle enough to use on the delicate tissues in your mouth.

In fact, the lack of side effects and toxicity is why many people are turning to nano hydroxyapatite toothpaste as a safe, non-toxic alternative to fluoride toothpaste.

Of course, there may be isolated cases of individual allergic reactions or sensitivities to certain ingredients in toothpaste, but because hydroxyapatite is the material our teeth and bones are already made of, this concern is exceedingly rare.

Overall, evidence suggests that hydroxyapatite toothpaste is a safe and effective option for maintaining oral health without any adverse effects.

Fluoride vs. Hydroxyapatite Toothpaste Side Effects

Fluoride vs. Hydroxyapatite Toothpaste Side Effects

While they do have equal efficacy when it comes to remineralizing and cleaning your teeth, there are notable differences in their potential side effects.

Hydroxyapatite toothpaste, as evidenced by a published study, demonstrates excellent safety and efficacy in promoting oral health. The study indicated that it has no reported adverse effects due to its excellent biocompatibility. Therefore it is safe to use by everyone, specially for children and pregnant women.

On the other hand, fluoride, when used in appropriate amounts, is generally safe and effective for strengthening teeth and promoting overall oral health. However, excessive fluoride consumption can lead to potential side effects which we'll review in this section.

Dental Fluorosis

Dental fluorosis is a condition that affects the appearance of tooth enamel, typically occurring during the early stages of tooth development in childhood.

It manifests as white streaks or spots, brown discoloration, or pitting on the tooth surface. Dental fluorosis occurs when children ingest too much fluoride during tooth formation, often from swallowing fluoride toothpaste or consuming fluoridated water in excess.

While mild forms of dental fluorosis may be barely noticeable, severe cases can lead to significant aesthetic concerns and may require cosmetic dental treatment to improve the appearance of affected teeth.

Skeletal Fluorosis

Skeletal fluorosis is a bone disorder caused by long-term exposure to high levels of fluoride, typically from drinking water with naturally occurring fluoride concentrations above recommended levels.

In skeletal fluorosis, fluoride accumulates in the bones, leading to changes in bone density and structure. Symptoms of skeletal fluorosis may include joint pain, stiffness, and skeletal deformities.

While skeletal fluorosis is rare in areas with controlled fluoride levels, it remains a concern in regions where natural fluoride levels are high or in populations with excessive fluoride exposure.

Fluoride Toxicity

Fluoride toxicity occurs when individuals ingest large amounts of fluoride, either accidentally or intentionally. This can happen through the ingestion of fluoride-containing products such as toothpaste or mouthwash, especially by young children who may swallow these products instead of spitting them out.

Symptoms of fluoride toxicity may include nausea, vomiting, abdominal pain, diarrhea, and in severe cases, convulsions and cardiac arrhythmias.

While acute fluoride toxicity is rare, it can occur in cases of accidental ingestion of concentrated fluoride products or intentional misuse of fluoride supplements.

Neurological Issue for Children

In addition to fluorosis, there are concerns about fluoride's potential links to other health issues, including neurological problems and a possible increased risk of certain fractures. Some studies have suggested that high fluoride levels may be associated with a lower IQ in children, though this research is subject to ongoing debate and requires further investigation. This is one of the most common reasons mothers choose to avoid fluoride.

Due to this controversy, we recommend that pregnant and nursing women brush with nano hydroxyapatite toothpaste, a better alternative to fluoride.

So, is hydroxyapatite safer than fluoride?

Hydroxyapatite vs Fluoride Toothpaste

Yes, hydroxyapatite is safer than fluoride toothpaste. Hydroxyapatite toothpaste has been shown to be as effective as fluoride in preventing tooth decay and may even be superior in treating tooth sensitivity, without causing adverse effects or toxic reactions.

Conversely, overuse of fluoride may lead to serious dental and overall health concerns, particularly in children. Therefore, when it comes to safety, considering hydroxyapatite toothpaste as an alternative is highly advisable.

Is nano hydroxyapatite as safe as hydroxyapatite?

The rod-shaped nano-sized hydroxyapatite particles have been found to be safe for use in toothpaste and show greater effectiveness in strengthening enamel compared to hydroxyapatite.

Additionally, in vitro study suggests that no cytotoxicity has been reported for rod-shaped nano hydroxyapatite toothpaste.

One paper from 2023 even stated, "Compared to HA, nHA is found to have superior properties such as increased solubility, high surface energy and better biocompatibility. This is due to the morphological and structural similarity of nanosized hydroxyapatite particles to tooth hydroxyapatite crystals."

Essentially, because nano hydroxyapatite particles are so small, they're better able to integrate into the tooth structure and remineralize enamel. Therefore, nano hydroxyapatite toothpastes provide a safe and great oral hygiene benefits over hydroxyapatite toothpastes.

Summary: Side Effects of Hydroxyapatite Toothpastes

All in all, hydroxyapatite toothpaste is considered to have no side effects. In fact, it is a beneficial alternative to traditional fluoride-based toothpaste, offering effective cleaning and enamel remineralization properties without the potential risks associated with fluoride, like:

  • dental fluorosis

  • skeletal fluorosis

  • fluoride intoxication

  • and neurological issues.

The safety profile of hydroxyapatite toothpaste makes it a suitable option for everyone, offering a natural and gentle oral care product.

Its ability to strengthen enamel, reduce sensitivity, and promote overall oral health without side effects contributes to its growing popularity among consumers looking for non-toxic dental care solutions.

In conclusion, the use of hydroxyapatite toothpaste is supported by research that highlights its efficacy and safety, making it a favorable choice for maintaining oral hygiene without the concern of adverse effects.

Frequently Asked Questions

Is hydroxyapatite in toothpaste safe?
Yes, hydroxyapatite in toothpaste is generally considered safe. It is a naturally occurring mineral that provides benefits such as strengthening tooth enamel and helping to prevent tooth decay. In fact, studies suggest that hydroxyapatite is effective in remineralizing teeth and reducing sensitivity. Additionally, hydroxyapatite is biocompatible with the human body, making it a safe ingredient for oral care products. Overall, toothpaste containing hydroxyapatite can be a safe and beneficial choice for maintaining your oral health without any adverse effect.

Do dentists recommend hydroxyapatite?
Yes, many dentists recommend hydroxyapatite toothpaste as an effective option for maintaining optimal oral health. Hydroxyapatite offers benefits such as enamel remineralization, reduction of sensitive teeth, and prevention of tooth decay, making it a valuable addition to dental hygiene routines. Moreover, it serves as a safe and effective alternative to fluoride, making it recommended by numerous dental professionals.

Did Europe ban hydroxyapatite?
No, hydroxyapatite is not banned in the EU. As of March 2023, the EU Scientific Committee of Consumer Safety determined that "hydroxyapatite (nano) [is] safe when used at concentrations up to 10% in toothpaste, and up to 0.465% in mouthwash." This indicates that hydroxyapatite is considered safe for use in oral care products within specified limits by regulatory authorities in the European Union.

Is hydroxyapatite bad for your teeth?
No, hydroxyapatite is not bad for your teeth. In fact, hydroxyapatite is a naturally occurring mineral that makes up a significant portion of your tooth enamel and bone. When used in toothpaste or other oral care products, hydroxyapatite can help to strengthen enamel, remineralize teeth, and protect against decay. It is considered safe and beneficial for maintaining your oral health.

Can I use hydroxyapatite toothpaste everyday?
Yes, you can use hydroxyapatite toothpaste every day as part of your oral hygiene routine. Hydroxyapatite toothpaste is safe for daily use and can help to strengthen enamel, remineralize teeth, and maintain overall oral health. We recommend to brush your teeth with hydroxyapatite toothpaste at least twice a day, preferably after meals, for optimal results.

NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets

NOBS Toothpaste Tablets

Regular price$40
Shipping calculated at checkout.

NOBS is everything toothpaste should be - all the good stuff, and none of the junk.

Fluoride Free
Never any fluoride, and no harsh abrasives.

We used the magical remineralizing power of 5% nano-hydroxyapatite to protect your teeth long-term. It's the safest alternative to fluoride!

Unlike messy tube toothpaste, NOBS are easy to store and use anywhere.

Thanks to our unique blend of natural ingredients, NOBS will make your breath as fresh as you look. Instead of gross sweeteners that cover up a natural slightly bitter aftertaste, our organic mint will leave you so kissable. Trust us, your date will thank you.

Cleans Effectively Without Damaging Enamel

With an enviable RDA of 21.38, NOBS Toothpaste Tablets are intentionally designed to help you gently buff out surface stains and break up plaque biofilm without causing damage to your enamel. Thanks, baking soda!

Flex on TSA

NOBS toothpaste tablets don’t apply to the 3.4oz limit. Fly with confidence that you won’t be condemned to a dirty mouth while you travel.

No Mess

Never worry about your toothpaste tube exploding over your other toiletries. NOBS toothpaste tablets come in an air-tight glass jar, free of plastic and without the mess. Unscrew, chew, and renew your mouth.

No Plastic

We want you to disrupt your brushing routine, not your endocrine system. Unlike other brands, our product is free of all plastics and BPAs.

Perfect Size

NOBS toothpaste tablets are individual and perfectly dosed. No more squeezing, no more tube sliding against the edge of your sink and definitely no wasted toothpaste.

Safe for Children

Protecting little ones is our top priority. NOBS provides the safest oral care for pregnant women and their families. Just monitor and ensure that your child can chew and swallow safely before introducing them to NOBS.

This product is not suitable for pets. Humans only, please!

While xylitol is great for supporting the human oral microbiome, it can be toxic to pets. Please keep NOBS away from your furry friends, and contact your veterinarian immediately if consumed by your pet.

Fluoride Free Toothpaste Tablets