Top 10 Hydroxyapatite Toothpaste Benefits

So, you may be familiar with hydroxyapatite toothpastes and how they're gaining popularity for their unique benefits.

But did you know that hydroxyapatite toothpaste helps fight tooth decay, kills harmful bacteria, whitens your teeth, and reduce hypersensitivity, all while protecting you from the negative side effects of fluoride?

It's true! Plus, hydroxyapatite toothpastes come without the risks of fluoride allergies, dental fluorosis, and fluoride intoxication.

In this article, we will explore the top 10 benefits of using hydroxyapatite toothpaste and debunk common misconceptions surrounding its effectiveness.

So, what is hydroxyapatite toothpaste?

A hydroxyapatite toothpaste tablets

Hydroxyapatite used in many forms including toothpaste, it is an innovative oral care product that harnesses the power of hydroxyapatite, a naturally occurring mineral found in your tooth enamel surface.

These hydroxyapatite toothpastes work by depositing calcium and phosphate ions back into your tooth surfaceResearch has shown that this can make your teeth stronger and help fill in minerals, which is good for your dental health.

It offers a fluoride-free alternative for maintaining your optimal oral health, making it suitable for individuals with fluoride sensitivities.

Additionally, hydroxyapatite toothpaste tablets are just equally as effective as traditional toothpaste but offer the added benefits of being better for the environment and more convenient for travel due to their compact and mess-free nature.

Hydroxyapatite Uses

While nano-hydroxyapatite was first patented for use in toothpaste by Sangi Co Ltd in 1978, it also has many different applications, such as:

  • Nano medical hydroxyapatite toothpaste: to promote a healthy enamel surface area
  • Bone grafts: to reconstruct periodontal bone defects
  • Crown bonding: to reinforce glass ionomers
  • Drug delivery systems: to improve medication bioavailability
  • Anti-tumor effects: to safely treat of cancers without adverse effects
  • Wound healing: to speed up the healing process by introducing calcium
  • Surface coating: to improve clinical outcomes associated with artificial implants
  • Scaffolding: to treat and correct bone defects

These hydroxyapatite uses play a crucial role in improving patient outcomes across various medical fields. Its biocompatibility and ability to mimic bone and enamel make it highly valuable in dentistry and regenerative medicine.

How does it work?

Hydroxyapatite toothpaste works through its ability to stimulate a process called remineralization. Essentially, hydroxyapatite particles restore and strengthen our tooth enamel by depositing calcium phosphate ions.

You see, when our enamel is exposed to acids produced by the bacteria that naturally live in our mouths or dietary acids/sugars, it can become demineralized. This leads to weakened enamel, tooth sensitivity, and tooth decay. If left untreated, that tooth decay can progress into full blown dental caries.

Since hydroxyapatite is a biomimetic compound and closely mimics the natural mineral composition of our teeth, it is easily able to remineralize enamel and protect us from all kinds of dental issues.

Plus, studies also show that hydroxyapatite toothpaste can prevent plaque buildup which can otherwise lead to tartar development and cavities. Further, more research suggests that hydroxyapatite can also whiten teeth as the tooth remineralization process may remove surface stains.

Is hydroxyapatite toothpaste safe?

A woman brushing her teeth

Yes, hydroxyapatite, alongside its smaller cousin nano hydroxyapatite, is safe to use in toothpaste. In fact, research indicates that nano hydroxyapatite toothpaste may have fewer safety concerns compared to fluoride toothpaste.

Nano hydroxyapatite particles and hydroxyapatite particles do not induce toxicity the way overconsumption of fluoride can. This is particularly important for certain populations such as:

  • pregnant women

  • children

  • people prone to tooth decay and cavities

  • people who live in environments with high fluoride concentrations in the water

This is likely because nano hydroxyapatite particles are biomimetic and safe as they are already a substance naturally present in our teeth, which makes them less likely to cause any harm when use.

Therefore, choosing nano hydroxyapatite toothpaste tablets can be your ideal step toward a safer and more effective oral care routine.

Now that we know hydroxyapatite toothpaste is safe to use in our daily oral care routine, let's review some of the benefits!

Benefit #1: Promotes Enamel Remineralization

A remineralizing teeth

Studies show that hydroxyapatite toothpaste promotes dental enamel remineralization, effectively repairing and strengthening your tooth enamel.

This natural mineral compound is able to reverse early enamel erosion and fight tooth decay by replenishing the essential minerals, such as calcium and phosphate.

In fact, in comparing hydroxyapatite vs fluoride, hydroxyapatite toothpaste is scientifically proven to be just as effective as fluoride at remineralizing teeth.

Benefit #2: Soothes Hypersensitivity

Hydroxyapatite toothpaste has its ability to soothe tooth sensitivity.

This toothpaste works by creating a protective layer over the exposed dentin, which reduces the transmission of external stimuli to the nerve endings, thereby lessening the pain associated with tooth sensitivity.

Plus, it can greatly enhance your ability to tolerate acidity, temperature, and sugar, ultimately improving your overall quality of life.

Benefit #3: Prevents Tooth Decay

a woman holding a tooth cavity model

While hydroxyapatite cannot reverse cavities, research indicates that hydroxyapatite does indeed help prevent tooth decay.

It works by inhibiting plaque-causing bacteria and remineralizing initial caries lesions, making it an effective option for preventing tooth decay.

Compared to fluoride toothpastes, hydroxyapatite toothpaste offers a natural alternative for preventing tooth decay. It provides similar cavity prevention benefits without the potential side effects of fluoride.

Benefit #4: Fights Plaque-Causing Bacteria

Studies indicate that hydroxyapatite toothpaste acts as a natural defense against plaque-causing bacteria, helping to prevent the formation of oral biofilm.

Unlike fluoride, hydroxyapatite has a unique antibacterial properties. By selectively killing off certain strains of bacteria that disrupt your mouth, hydroxyapatite protects your teeth and gums.

Additionally, hydroxyapatite disrupts biofilm, thereby reducing your risk of developing demineralization and gum issues.

Benefit #5: Naturally Compatible with Your Teeth

Another remarkable benefit of hydroxyapatite toothpaste is its natural compatibility with your teeth.

Because the composition of hydroxyapatite closely resembles the minerals found in tooth enamel, it provides your teeth with the necessary minerals making it an ideal choice for maintaining healthy enamel.

Plus, unlike other toothpaste options, hydroxyapatite does not introduce foreign substances to your teeth.

Benefit #6: Safe Alternative to Fluoride

A family brushing their teeth

If you are aware of the potential risks associated with fluoride, you'll be excited to hear studies have shown that hydroxyapatite toothpaste provides a safe and effective alternative.

Fluoride toothpastes have been widely used for decades to prevent tooth decay. However, research indicates that excessive fluoride consumption, especially during early childhood, can lead to dental fluorosis and toxicity.

Hydroxyapatite toothpaste, on the other hand, does not contain fluoride, but offers comparable efficacy in reversing tooth decay, strengthening the teeth, and inhibiting the growth of plaque-causing bacteria.

Because hydroxyapatite toothpaste side effects are minimal, they're a great tool for pregnant women and children to use.

Benefit #7: Fights Dental Caries

An oral bacterial

Hydroxyapatite toothpaste offers an effective solution in the fight against dental caries.

Through its unique composition, this toothpaste can remineralize and strengthen your weakened tooth structures, effectively combatting caries lesions and preventing further damage.

This preventive dentistry approach is particularly valuable in reducing the risk of tooth loss and the need for extensive dental treatments. By using hydroxyapatite toothpaste regularly, you can actively support your oral health and protect your teeth from the harmful effects of dental caries.

Benefit #8: Promotes Good Oral Health

Hydroxyapatite toothpaste promotes good oral health by addressing various dental concerns effectively.

Studies have shown that hydroxyapatite enhances enamel remineralization, strengthens tooth structure, and inhibits the growth of plaque-causing bacteria.

It has natural antibacterial properties contribute to a healthier oral environment, reducing the risk of gum disease and other oral infections.

Therefore, by incorporating hydroxyapatite toothpaste into your daily oral care routine, you can effectively protect your gums, prevent oral diseases, and maintain strong, healthy teeth.

Benefit #9: Brightens Teeth

Hydroxyapatite toothpaste also offers the benefit of brightening teeth through its gentle and effective stain removal properties.

An in vitro study states that hydroxyapatite toothpaste effectively removes surface stains from teeth, resulting in a brighter and whiter smile.

Unlike abrasive whitening toothpaste that may contain SLS and can cause enamel damage, hydroxyapatite toothpaste gently polishes the teeth, revealing their natural brightness without compromising enamel integrity.

This fluoride-free toothpaste is an excellent option for people with sensitive teeth who may experience discomfort or sensitivity when using traditional whitening products.

To experience the whitening effects of hydroxyapatite toothpaste, incorporate it into your daily oral care routine. Brushing your teeth twice a day with this natural toothpaste can help you achieve a radiant smile while promoting overall oral health.

Benefit #10: Stabilizes Your Oral pH

Hydroxyapatite toothpaste offers the distinct advantage of stabilizing your oral pH, contributing to a healthier mouth environment.

Research indicates that hydroxyapatite is resistant to acid, allowing it to effectively buffer the pH levels in your mouth. This means that even when acidic substances are consumed, such as citrus fruits or carbonated beverages, hydroxyapatite can help maintain a more neutral pH, reducing the risk of enamel erosion and promoting overall oral health.

By stabilizing your oral pH, hydroxyapatite toothpaste aids in preserving tooth enamel and minimizing the likelihood of dental issues like cavities and tooth sensitivity.

Therefore, incorporating hydroxyapatite toothpaste into your oral care routine can lead to a more balanced and resilient oral environment, supporting long-term dental wellness.

How to Use Hydroxyapatite Toothpaste Tablets

A woman brushing her teeth

To use hydroxyapatite toothpaste tablets, you should following this simple steps:

  1. Pop one tablet in your mouth - one tablet is all that you need. Each tablet is perfectly sized and dosed, just enough amount that you need in one brush.

  2. Chew it - chew the tablet until it dissolves in your mouth and forms a paste by mixing it with your saliva.

  3. Grab your toothbrush - ensure it is wet by running it in water for a second or dipping it in a glass of water.

  4. Brush your teeth as you regularly do - it's that simple.

Just keep in mind that you don't need to rinse after brushing teeth. Just go ahead and spit out the excess to allow the nano hydroxyapatite to work its magic and remineralize your teeth.

Hydroxyapatite vs. Nano Hydroxyapatite Toothpaste

Both nano hydroxyapatite and hydroxyapatite are forms of the same naturally occurring mineral that makes up our teeth and bones. Recently, they've both been making waves in regenerative dentistry as alternatives to fluoride.

However, in comparing hydroxyapatite vs nano hydroxyapatite, one research paper stated that nano hydroxyapatite toothpaste tends to be more superior and effective at:

  • fighting tooth decay

  • remineralizing enamel

  • and soothing hypersensitivity,

due to its smaller particle size, which allows for better penetration, high surface energy, and adhesion to tooth enamel.

That said, while nano hydroxyapatite is more effective in toothpaste than hydroxyapatite, hydroxyapatite has a broader range of applications such as more frequent use in orthopedic implants and bone grafts.

Essentially, because hydroxyapatite nanoparticles are so small, they're better able to integrate into the tooth structure and remineralize enamel. Therefore, nano hydroxyapatite toothpastes provide increased oral hygiene benefits over hydroxyapatite toothpastes.

Hydroxyapatite Toothpaste vs. Fluoride Toothpaste

In comparing hydroxyapatite vs fluoride, they're both popular choices for maintaining dental health, but they differ in many ways.

Fluoride toothpaste contains fluoride, a mineral known for its ability to strengthen enamel and prevent tooth decay by remineralizing weakened areas of the teeth. On the other hand, hydroxyapatite toothpaste utilizes hydroxyapatite, a naturally occurring mineral that mimics the composition of tooth enamel.

While both have same efficacy, hydroxyapatite can be considered better than fluoride as it offers similar benefits without the associated toxicity.

It provides the advantages of fluoride, such as enamel protection, sensitivity reduction, and remineralization, but without the potential harm linked to fluoride ingestion. For example, research suggests that hydroxyapatite is non-toxic and safe enough to swallow, unlike fluoride which can cause dental and skeletal fluorosis if overexposed.

That's why we recommend choosing hydroxyapatite toothpaste - it can be a safer and better alternative for oral care.

Summary: Hydroxyapatite Benefits

A NOBS Toothpaste Tablets

To sum up, hydroxyapatite toothpaste offers numerous benefits for oral health.

From promoting dental enamel remineralization and reducing tooth sensitivity to preventing tooth decay and maintaining gum health, hydroxyapatite provides a natural and effective solution.

Additionally, it offers a fluoride-free option, making it suitable for individuals with fluoride sensitivities or those seeking an alternative.

With its eco-friendly formulations, convenient, sustainable toothpaste tablets, hydroxyapatite toothpaste is a versatile choice for maintaining optimal your oral hygiene and overall dental wellness.

Frequently Asked Questions

What is hydroxyapatite?
Hydroxyapatite is a naturally occurring mineral that makes up the majority of tooth enamel and bone. In dental products, it helps repair and remineralize enamel by mimicking the mineral structure of teeth. It's commonly used as an alternative to fluoride for strengthening and protecting enamel.

Are there any side effects of using hydroxyapatite toothpaste?
Studies show that hydroxyapatite toothpaste is safe and well-tolerated, with no reported side effects. A 2019 review in Biomaterials found that hydroxyapatite is biocompatible, meaning it integrates well with natural tooth structures without causing harm. Another study confirmed that hydroxyapatite toothpaste is effective for enamel remineralization and cavity prevention, with no adverse effects noted in long-term use.

Can I use hydroxyapatite toothpaste everyday?
Yes, you can use hydroxyapatite toothpaste every day as part of your regular oral hygiene routine. In fact, using it consistently can help promote enamel remineralization, strengthen tooth structure, and maintain overall oral health.

Do dentists recommend hydroxyapatite?
Yes, many dentists recommend hydroxyapatite toothpaste as an effective option for maintaining optimal oral health. Hydroxyapatite offers benefits such as enamel remineralization, reduction of sensitive teeth, and prevention of tooth decay, making it a valuable addition to dental hygiene routines. Moreover, it serves as a safe and effective alternative to fluoride, making it recommended by numerous dental professionals.

How long to leave hydroxyapatite on teeth?
We recommend to leave hydroxyapatite on your teeth for about 20-30 minutes before eating or drinking for optimal effectiveness. This allows the hydroxyapatite to have more time to interact with the tooth surface and promote enamel remineralization.

Can hydroxyapatite whiten teeth?
Yes, hydroxyapatite toothpaste can whiten your teeth by effectively removing surface stains over time. Unlike traditional whitening toothpaste that can be bad for you due to its abrasiveness and may cause sensitivity, hydroxyapatite toothpaste has a whitening properties that offers a gentle approach to brightening your smile while promoting enamel remineralization and overall oral health. With consistent use, you can achieve a naturally brighter and healthier-looking smile without the risk of sensitivity.

Should you rinse after hydroxyapatite?
It is not necessary to rinse your mouth with water after using hydroxyapatite toothpaste. Instead, we recommend you spit out any excess paste and allow the hydroxyapatite to remain on your teeth for about 20-30 minutes before eating or drinking for optimal effectiveness.


NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets
NOBS Toothpaste Tablets

NOBS Toothpaste Tablets

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NOBS is everything toothpaste should be - all the good stuff, and none of the junk.

Fluoride Free
Never any fluoride, and no harsh abrasives.

We used the magical remineralizing power of 5% nano-hydroxyapatite to protect your teeth long-term. It's the safest alternative to fluoride!

Unlike messy tube toothpaste, NOBS are easy to store and use anywhere.

Thanks to our unique blend of natural ingredients, NOBS will make your breath as fresh as you look. Instead of gross sweeteners that cover up a natural slightly bitter aftertaste, our organic mint will leave you so kissable. Trust us, your date will thank you.

Cleans Effectively Without Damaging Enamel

With an enviable RDA of 21.38, NOBS Toothpaste Tablets are intentionally designed to help you gently buff out surface stains and break up plaque biofilm without causing damage to your enamel. Thanks, baking soda!

Flex on TSA

NOBS toothpaste tablets don’t apply to the 3.4oz limit. Fly with confidence that you won’t be condemned to a dirty mouth while you travel.

No Mess

Never worry about your toothpaste tube exploding over your other toiletries. NOBS toothpaste tablets come in an air-tight glass jar, free of plastic and without the mess. Unscrew, chew, and renew your mouth.

No Plastic

We want you to disrupt your brushing routine, not your endocrine system. Unlike other brands, our product is free of all plastics and BPAs.

Perfect Size

NOBS toothpaste tablets are individual and perfectly dosed. No more squeezing, no more tube sliding against the edge of your sink and definitely no wasted toothpaste.

Safe for Children

Protecting little ones is our top priority. NOBS provides the safest oral care for pregnant women and their families. Just monitor and ensure that your child can chew and swallow safely before introducing them to NOBS.


This product is not suitable for pets. Humans only, please!

While xylitol is great for supporting the human oral microbiome, it can be toxic to pets. Please keep NOBS away from your furry friends, and contact your veterinarian immediately if consumed by your pet.

Fluoride Free Toothpaste Tablets

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